Mouse Monoclonal Antibody [2F9] to GlucagonThe protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]
Immunogen
The immunogen corresponding to human Glucagon expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2F9
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
GLP2 GRPP GLP1
Target
Glucagon
Molecular Weight(MW)
21 kDa (note)
Application
Application
Western blot analysis using GCG mAb against HEK293 (1) and GCG (AA: 1-180)-hIgGFc transfected HEK293 (2) cell lysate.