| Product Name | IL1 Receptor 2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [4T28] to IL-1 R2The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012] |
| Immunogen | Human recombinant IL1-R II EC domain |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 4T28 |
| Host Species | Mouse |
| Tested Applications | IHCNeutWB |
| WB(1:500-2000)|IHC (frozen)(1:20-200)|Neutralization of IL-1 RII mediated bioactivity: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | IL-1RT2 IL1RB CD121b IL1R2 IL1R2c IL-1R-2 IL-1RT-2 interleukin 1 receptor type II CDw121b |
|---|---|
| Target | IL-1 R II |
| Tissue Specificity | This antibody was selected for its ability to detect human IL-1 R2. |
| Application Notes | WB(1:500-2000)|IHC (frozen)(1:20-200)|Neutralization of IL-1 RII mediated bioactivity: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
