| Product Name | IL6 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [1X45] to IL6This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011] |
| Immunogen | Human recombinant IL-6 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 1X45 |
| Host Species | Mouse |
| Tested Applications | IHCNeut |
| WB(1:500-2000)|IHC (frozen)(1:20-100)|Neutralization of IL-6 bioactivity: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HSF interleukin 6 (interferon beta 2) HGF BSF2 IL6 IFNB2 |
|---|---|
| Target | IL6 |
| Tissue Specificity | This antibody was selected for its ability to detect human IL-6. |
| Application Notes | WB(1:500-2000)|IHC (frozen)(1:20-100)|Neutralization of IL-6 bioactivity: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
