Mouse monoclonal antibody [9D7] to MATKThe protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Immunogen
The immunogen corresponding to human MATK expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
9D7
Host Species
Mouse
Tested Applications
ELISAFACSWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Target Information
Gene Synonyms
HHYLTK CHK CTK HYLTK LSK HYL
Target
MATK
Molecular Weight(MW)
56 kDa (note)
Application
Application
Western blot analysis using anti-MATK mAb against K562 cell lysate (1).
Application
Flow cytometric analysis of K562 cells using anti-MATK mAb (green) and negative control (purple).
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.
Storage Buffer
Antibody are purified by protein G affinity chromatography. Liquid in PBS containing 50% glycerol and 0.03% sodium azide.