Application
IHC-P analysis of rat cardiac muscle using Nav1.5 antibody at a dilution of 1:100.Application
WB analysis of Nav1.5 transfected HEK293 lysates using Nav1.5 antibody at a dilution of 1:200 in the (1) absence or (2) presence of blocking peptide.| Product Name | Nav1.5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Nav1.5The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Immunogen | GST fusion protein with amino acid residues 1978-2016 of human Nav1.5 (Accession# Q14524), (MW: 33 kDa.). Intracellular, C-terminus. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | FACSICC/IFIHC-PWB |
| FACS:1:200~1:500 ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HB2 HBBD SSS1 HB1 PFHB1 SCN5A VF1 CDCD2 HH1 LQT3 CMD1E ICCD IVF sodium channel voltage-gated type V alpha sub |
|---|---|
| Target | Nav1.5 |
Application
IHC-P analysis of rat cardiac muscle using Nav1.5 antibody at a dilution of 1:100.
Application
WB analysis of Nav1.5 transfected HEK293 lysates using Nav1.5 antibody at a dilution of 1:200 in the (1) absence or (2) presence of blocking peptide.| Application Notes | FACS:1:200~1:500 ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The reconstituted solution can be stored at 4°C for up to 2 weeks. For longer periods, small aliquots should be stored at -20°C or below. Avoid multiple freezing and thawing. |
| Storage Buffer | Phosphate buffered saline (PBS), pH 7.4, 1% BSA and 0.05% NaN3. |
