WB
mouse heart tissue were subjected to SDS PAGE followed by western blot with Nav1.5 antibody at dilution of 1:600 incubated at room temperature for 1.5 hours.IHC
Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using Nav1.5 antibody at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).IHC
Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using Nav1.5 antibody at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).| Product Name | Nav1.5 Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant human SCN5A protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:500-1:1000 IHC:1:50-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SCN5A |
|---|---|
| Gene Synonyms | HB1 HB2 HH1 IVF VF1 HBBD ICCD LQT3 SSS1 CDCD2 CMD1E CMPD2 PFHB1 Nav1.5 |
| Gene Full Name | sodium voltage-gated channel alpha subunit 5 |
| Gene Summary | The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene have been associated with long QT syndrome type 3 (LQT3), atrial fibrillation, cardiomyopathy, and Brugada syndrome 1, all autosomal dominant cardiac diseases. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, May 2022] |
| Alternative Names | Nav1.5 1C2B3 CDCD2 CMD1E CMPD2 |
| Molecular Weight(MW) | 227 kDa |
| Cellular Localization | Cell junction,Cell membrane,Cytoplasm,Membrane. |
WB
mouse heart tissue were subjected to SDS PAGE followed by western blot with Nav1.5 antibody at dilution of 1:600 incubated at room temperature for 1.5 hours.
IHC
Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using Nav1.5 antibody at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
IHC
Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using Nav1.5 antibody at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).| Application Notes | WB:1:500-1:1000 IHC:1:50-1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C. Stable for one year after shipment. |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
