| Product Name | NQO1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [AI80] to NQO1This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized |
| Immunogen | Full length purified recombinant human NQO1 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | AI80 |
| Host Species | Mouse |
| Tested Applications | IHC-PIPWB |
| For WB: Use at 1:2000: |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | NAD(P)H dehydrogenase quinone 1 DTD QR1 DHQU DIA4 |
|---|---|
| Target | NQO1 |
| Tissue Specificity | Human & Rat NQ01. Does not react with mouse NQO1 |
| Application Notes | For WB: Use at 1:2000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 2-8°C. For extended storage, aliquot and store at -20°C. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | PBS + 0.1% sodium azide |
