Application
IHC-P analysis of human lung carcinoma tissue using OAS1 antibody at a dilution of 1:200.| Product Name | OAS1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to OAS1This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml): |
|
| Species Reactivity | HumanMousePig |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | OIAS IFI-4 2'-5'-oligoadenylate synthetase 1 40/46kDa OIASI |
|---|---|
| Target | OAS1 |
Application
IHC-P analysis of human lung carcinoma tissue using OAS1 antibody at a dilution of 1:200.| Application Notes | P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
| Storage Buffer | 10 mM PBS, pH 7.4 with 10 mg/ml BSA and 0.1% sodium azide |
