Western blot analysis using anti-PARL monoclonal antibody against truncated Trx-PARL recombinant protein(1) and truncated MBP-PARL(aa112-167) recombinant protein(2).
Mouse monoclonal antibody [8C4B2;1H12E10] to PARLThis gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Immunogen
The immunogen corresponding to a region within amino acids 112 and 167 of PARL expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG2
Clone Number
8C4B2;1H12E10
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
PSARL1 PSARL PSENIP2 PRO2207 RHBDS1
Target
PARL
Cellular Localization
Translocated into the nucleus by an unknown mechanism.
Application
Application
Western blot analysis using anti-PARL monoclonal antibody against truncated Trx-PARL recombinant protein(1) and truncated MBP-PARL(aa112-167) recombinant protein(2).
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.