Mouse monoclonal antibody [1C8] to PAX6This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Immunogen
The immunogen corresponding to human PAX6 expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1C8
Host Species
Mouse
Tested Applications
ELISAICC/IFWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
WAGR D11S812E AN2 AN MGDA
Target
PAX6
Molecular Weight(MW)
46 kDa (note)
Application
Application
Flow cytometric analysis of 3T3-L1 cells using PAX6 mouse mAb (green) and negative control (purple)
Application
Western blot analysis using PAX6 mAb against human PAX6 (AA: 1-223) recombinant protein. (Expected MW is 50 kDa)
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.