Caspase 3 is synthesized as an inactive proenzyme that undergoes proteolytic cleavage to produce 2 subunits, termed p20 and p11. These subunits dimerize to form the active enzyme. Caspase 3 proteolytically cleaves and activates other proteins. Caspase 3 has been associated with apoptosis.
Immunogen
Caspase-3 antibody was raised against a peptide mapping to the amino terminal domain of Caspase-3 (Human).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIPWB
Caspase-3 antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.: