| Product Name | CD284 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TOLL, CD284, TLR-4, ARMD10, TLR4 |
| Product description | The HTA125 monoclonal antibody specifically reacts with human CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4). CD284 is an important molecule in the innate immunity response to bacterial lipoproteins. It is expressed by monocytes, macrophages, and endothelial cells. The HTA125 antibody can block Lipopolysaccharide-induced cytokine production and immunoprecipitate human TLR4.1) Akashi, S., Ogata, H., Kirikae, F., Kirikae, T., Kawasaki, K., Nishijima, M., ... Miyake, K. (2000). Regulatory roles for CD14 and phosphatidylinositol in the signaling via toll-like receptor 4-MD-2.Biochemical and biophysical research communications,268(1), 172-177. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a,k |
| Host Species | Mouse |
| Tested Applications | FACSFunctionalStudies |
| FACS:1:200~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TLR4 |
|---|---|
| Alternative Names | TOLL CD284 TLR-4 ARMD10 TLR4 |
| Tissue Specificity | The HTA125 monoclonal antibody specifically reacts with human CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4). |
| Entrez Gene | 7099 |
|---|
| Application Notes | FACS:1:200~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The product should be stored undiluted at 4˚C . Do not freeze. |
| Storage Buffer | Phosphate-buffered aqueous solution, ph7.2. |
