FOXO1, FKHR, Forkhead in rhabdomyosarcoma, FOXO1A, FKH1, Forkhead box protein O1, Forkhead box protein O1A, Forkhead box O1, Forkhead box o1a, Forkhead domain protein fkhr
Product description
This antibody recognizes human FKHR (Forehead in Rhabdomyosarcoma), a 70 Kd protein that is a member of a subfamily of the forkhead homeotic gene family of transcription factors. Recent studies have shown that this protein can act as either a co-activator or a co-repressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the C-terminus of the FKHR protein. This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
Immunogen
FOXO1 monoclonal antibody was raised against amino acids 242 - 655 of FOXO1 (Human).
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Host Species
Mouse
Tested Applications
IHCWB
FOXO1 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, immunofluorescence starting at 1:200 - 1:1000, and flow cytometry starting at 1:200 - 1:400.:
Immunohistochemistry staining of FOXO1 in skeletal muscle tissue using FOXO1 monoclonal Antibody.
Application Notes
FOXO1 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, immunofluorescence starting at 1:200 - 1:1000, and flow cytometry starting at 1:200 - 1:400.:
Additional Information
Form
Liquid
Storage Instructions
Store FOXO1 antibody at -20 ˚C. As with all antibodies avoid freeze/thaw cycles.