Application
Immunohistochemistry staining of GLI2 in mouse, testis tissue using GLI2 Antibody.Application
Immunohistochemistry staining of GLI2 in mouse, brain using GLI2 Antibody.| Product Name | GLI2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GLI2, GLI-Kruppel family member GLI2, HPE9, Gli-2, Oncogene GLI2, Tax helper protein 2, THP, Zinc finger protein GLI2, Tax helper protein, THP2, GLI family zinc finger 2, Tax helper protein 1, THP1 |
| Product description | Gli-2 (also known as Zinc Finger Protein Gli-2, GLI-Kruppel family member GLI-2 or Tax helper protein) belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors that bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling, and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. Gli-2 is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes: Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, pre-axial polydactyly type IV, post-axial polydactyly types A1 and B. Expression has been reported for this mRNA in human testis, myometrium, kidney, lung, glioblastomas, and embryonal cell carcinomas. Multiple splice variants have been reported for this protein. |
| Immunogen | GLI2 antibody was raised against amino acids from an internal region of GLI2 (Mouse). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| GLI2 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 5 μg/mL.: |
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| Species Reactivity | Mouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GLI2 |
|---|---|
| Alternative Names | GLI2 GLI-Kruppel family member GLI2 HPE9 Gli-2 Oncogene GLI2 Tax helper protein 2 THP Zinc finger protein GLI2 Tax helper protein THP2 GLI family zinc finger 2 Tax helper protein 1 THP1 |
Application
Immunohistochemistry staining of GLI2 in mouse, testis tissue using GLI2 Antibody.
Application
Immunohistochemistry staining of GLI2 in mouse, brain using GLI2 Antibody.| Application Notes | GLI2 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 5 μg/mL.: |
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| Form | Liquid |
|---|---|
| Storage Instructions | Store GLI2 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide. |
