Application
Immunohistochemistry staining of GLI2 in skin tissue using GLI2 Antibody.| Product Name | GLI2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GLI2, GLI-Kruppel family member GLI2, HPE9, Gli-2, Oncogene GLI2, Tax helper protein 2, THP, Zinc finger protein GLI2, Tax helper protein, THP2, GLI family zinc finger 2, Tax helper protein 1, THP1 |
| Product description | Gli-2 (also known as Zinc Finger Protein Gli-2, GLI-Kruppel family member GLI-2 or Tax helper protein) belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors that bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. Gli-2 is a nuclear protein thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes; Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. Multiple splice variants have been reported for this protein. |
| Immunogen | Amino acids 46-60 of human Gli-2 (isoform a). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| GLI2 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 μg/mL.: |
|
| Species Reactivity | ChimpanzeeHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GLI2 |
|---|---|
| Alternative Names | GLI2 GLI-Kruppel family member GLI2 HPE9 Gli-2 Oncogene GLI2 Tax helper protein 2 THP Zinc finger protein GLI2 Tax helper protein THP2 GLI family zinc finger 2 Tax helper protein 1 THP1 |
Application
Immunohistochemistry staining of GLI2 in skin tissue using GLI2 Antibody.| Application Notes | GLI2 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store GLI2 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide. |
