*This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. EDTA pH8.0 is recommended for this purpose. IHC Control: Breast Carcinoma.
Immunogen
MDM2 monoclonal antibody was raised against amino acids 154 - 167 of MDM2 (Human).
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Host Species
Mouse
Tested Applications
IHCIPWB
MDM2 antibody can be used in immunohistochemistry starting at 1:50, and flow cytometry starting at 1 ug/1E6 cells.
MDM2 ACTFS Double minute 2 protein Hdm2 MDM2 variant FB30 HDMX Oncoprotein Mdm2 p53-binding protein Mdm2 MDM2 variant FB28
Tissue Specificity
Recognizes the 90kD MDM2 protein, which forms a complex with p53 leading to p53 inhibition. MDM2 also acts to stimulate cell proliferation via its induction of transcription factors such as E2F1 and DPI. MDM2 is over expressed in a range of human mal ...