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NR0B1 Antibody

Catalog Number:OM286510
OM286510
Discount Price
OM286510-100ul
1~2 Week
100ul
OM286510-50ul
50ul
OM286510-20ul
20ul
1~2 Week
Product Profile
Product Name NR0B1 Antibody
Antibody Type Primary Antibodies
Antigen Alias NR0B1, AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1, SRXY2
Product description NR0B1 is a protein that contains a DNA-binding domain. The protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in its gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.1) Mantovani, G., (2005) Fertil. Steril. 84 (5), 1542-1544.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR0B1.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAWB
NR0B1 antibody can be used for detection of NR0B1 by ELISA at 1:312500. NR0B1 antibody can be used for detection of NR0B1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol NR0B1
Alternative Names NR0B1
AHC
AHCH
AHX
DAX-1
DAX1
DSS
GTD
HHG
NROB1
SRXY2
Molecular Weight(MW) 52 kDa
Database Links
Entrez Gene 190
Protein Accession NP_000466
Application

Application

Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.
Positive Control 1) Cat. No. 1211 - HepG2 Cell Lysate
Application Notes NR0B1 antibody can be used for detection of NR0B1 by ELISA at 1:312500. NR0B1 antibody can be used for detection of NR0B1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store NR0B1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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