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Anti-Cav1.2/1.3 Ca2+ channel Antibody

Catalog Number:OM645371
OM645371
Discount Price
OM645371-100ul
100ul
Product Profile
Product Name Anti-Cav1.2/1.3 Ca2+ channel Antibody
Antibody Type Primary Antibodies
Key Feature
Clonality Monoclonal
Isotype IgG2a,k
Host Species Mouse
Tested Applications IHCWB
WB:1:500-1:2000
IHC:1:50-1:500
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CACNA1C
Gene Synonyms TS
LQT8
CACH2
CACN2
CaV1.2
CCHL1A1
NEDHLSS
CACNL1A1
TS. LQT8
CACNA1C-IT2
Gene Full Name calcium voltage-gated channel subunit alpha1 C
Gene Summary This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]
Molecular Weight(MW) 248 kDa
Cellular Localization Cell membrane.
Application

SDS-PAGE

SDS-PAGE for Anti-Cav1.2/1.3 Ca2+ channel Antibody.
Application Notes WB:1:500-1:2000
IHC:1:50-1:500
Additional Information
Form Liquid
Storage Instructions Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Storage Buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
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