DAB staining on IHC-P; Samples: Human Breast cancer Tissue; Primary Ab: 20µg/ml Mouse Anti-Human AREG Antibody Second Ab: 2µg/mL HRP Linked Caprine Anti-Mouse IgG Polyclonal Antibody.
Recombinant AREG (Ser20~Asp100) expressed in E.coli.
Key Feature
Clonality
Polyclonal
Isotype
IgG2b,k
Host Species
Mouse
Tested Applications
IHCWB
IHC:5-20µg/mL WB:1:200-1:2000
Species Reactivity
Human
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
AREG
Gene Synonyms
AR SDGF AREGB CRDGF
Gene Full Name
amphiregulin
Gene Summary
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]
Alternative Names
AR CRDGF SDGF Colorectum Cell-Derived Growth Factor Schwannoma-Derived Growth Factor
Molecular Weight(MW)
41kDa
Application
WB
Western Blot A. Sample: Recombinant AREG, Human.
IHC
DAB staining on IHC-P; Samples: Human Breast cancer Tissue; Primary Ab: 20µg/ml Mouse Anti-Human AREG Antibody Second Ab: 2µg/mL HRP Linked Caprine Anti-Mouse IgG Polyclonal Antibody.
Application Notes
IHC:5-20µg/mL WB:1:200-1:2000
Additional Information
Form
Liquid
Storage Instructions
Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months.
Storage Buffer
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.