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Mouse Monoclonal antibody to p-CaMKII

Catalog Number:OM646683
OM646683
Discount Price
OM646683-100ul
100ul
Product Profile
Product Name Mouse Monoclonal antibody to p-CaMKII
Antibody Type Primary Antibodies
Immunogen raised against a synthetic peptide corresponding to residues 281-294 CaM kinase II α subunit of rat origin.
Modification p-Thr286
Key Feature
Clonality Monoclonal
Isotype IgG1, k
Host Species Mouse
Tested Applications WB
WB:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 0.1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CAMK2A
Gene Synonyms CAMKA
MRD53
MRT63
CaMKIIalpha
CaMKIINalpha
Gene Full Name calcium/calmodulin dependent protein kinase II alpha
Gene Summary The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2018]
Molecular Weight(MW) 50 kDa
Cellular Localization Cell projection,Synapse.
Application

WB

p-CaMKII:Mouse Monoclonal antibody to p-CaMKII. Western blot analysis of CaMKII phosphorylation in untreated (A) and lambda phosphatase treated (B) rat brain tissue extract.

WB

p-CaMKII HRP:Mouse Monoclonal antibody to p-CaMKII.Direct western blot analysis of CaMKII phosphorylation in Sol8 whole cell lysate.
Application Notes WB:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required.
Storage Buffer Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
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