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Polyclonal Antibody to Phosphodiesterase 4B, cAMP Specific (PDE4B)

Catalog Number:OM646927
OM646927
Discount Price
OM646927-100ul
100ul
Product Profile
Product Name Polyclonal Antibody to Phosphodiesterase 4B, cAMP Specific (PDE4B)
Antibody Type Primary Antibodies
Immunogen Recombinant PDE4B (Lys500~Thr736) expressed in E.coli.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCWB
WB:0.01-2µg/mL
IHC:5-20µg/mL
Species Reactivity HumanMouseRat
Concentration 0.5mg/ml
Purification Protein A
Target Information
Gene Symbol PDE4B
Gene Synonyms DPDE4
PDEIVB
Gene Full Name phosphodiesterase 4B
Gene Summary This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Alternative Names DPDE4
PDE32
Dunce(Drosophila)Homolog Phosphodiesterase E4
cAMP-specific 3'
5'-cyclic phosphodiesterase 4B
Cellular Localization Cell membrane,Cytoplasm,Membrane.
Application

WB

Figure. Western Blot; Sample: Recombinant PDE4B, Rat.

IHC

DAB staining on IHC-P; Samples: Rat Testis Tissue; Primary Ab: 10µg/ml Rabbit Anti-Rat PDE4B Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody .

WB

Western Blot; Sample: Rat Cerebrum lysate; Primary Ab: 1µg/ml Rabbit Anti-Rat PDE4B Antibody. Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Application Notes WB:0.01-2µg/mL
IHC:5-20µg/mL
Additional Information
Form Liquid
Storage Instructions Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months.
Storage Buffer Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
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