WB
Western Blot; Sample: Lane1: Rat Cerebrum lysate; Lane2: Rat Cerebellum.| Product Name | Monoclonal Antibody to Phosphodiesterase 4B, cAMP Specific (PDE4B) |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant PDE4B (Lys500~Thr736) expressed in E.coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1, k |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:0.5-2µg/mL |
|
| Species Reactivity | Rat |
| Concentration | 1mg/ml |
| Purification | Protein A/G |
| Gene Symbol | PDE4B |
|---|---|
| Gene Synonyms | DPDE4 PDEIVB |
| Gene Full Name | phosphodiesterase 4B |
| Gene Summary | This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014] |
| Alternative Names | DPDE4 PDE32 Dunce(Drosophila)Homolog Phosphodiesterase E4 cAMP-specific 3' 5'-cyclic phosphodiesterase 4B |
| Cellular Localization | Cell membrane,Cytoplasm,Membrane. |
WB
Western Blot; Sample: Lane1: Rat Cerebrum lysate; Lane2: Rat Cerebellum.| Application Notes | WB:0.5-2µg/mL |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. |
| Storage Buffer | Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol. |
