All products Antibodies Anti-Cdk4 antibody

Anti-Cdk4 antibody

Catalog Number：OM642228

  • Western blot analysis using Cdk4 antibody against THP-1(1), K562(2) cell lysate.

  • Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using Cdk4 antibody with DAB staining.

  • Immunofluorescence analysis of Hela cells using Cdk4 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Product Profile

Product Name Anti-Cdk4 antibody
Antibody Type Primary Antibodies
Immunogen 
Polypeptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Protein A

Target Information

Gene Symbol CDK4
Gene Synonyms
CMM3
PSK-J3
Gene Full Name cyclin dependent kinase 4
Gene Summary
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 34 kDa
Cellular Localization Cytoplasm, Membrane, Nucleus

Application

  • WB

    Western blot analysis using Cdk4 antibody against THP-1(1), K562(2) cell lysate.

  • IHC

    Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using Cdk4 antibody with DAB staining.

  • ICC/IF

    Immunofluorescence analysis of Hela cells using Cdk4 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500

Additional Information

Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM642228
  • Price: $336.00
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  • Store: Out of stock
  • Lead time: 4~6 Week

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