CDK4 Antibody

Product Profile

Product Name	CDK4 Antibody
Antibody Type	Primary Antibodies
Product description	CDK4, a CDC2/CDK-type protein kinase, regulates cell cycle G1 phase progression. CDK4 associates with and is regulated by D-type cyclins and the CDK inhibitor p16 (CDKN2A). Two alternatively spliced variants have been reported. CDK4 has been shown to phosphorylate the retinoblastoma protein, and mutations in the CDK4 gene have been linked to tumorigenesis in several types of cancers, including cutaneous malignant melanoma.
Immunogen	CDK4 antibody was raised against a peptide mapping to the carboxy terminus of CDK4 (Mouse).

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	IHCIPWB
	CDK4 antibody can be used in ELISA starting at 1: 10000, Western Blot starting at 1: 500 - 1: 2000, immunohistochemistry starting at 1:200, and immunofluorescence starting at 1:200 - 1:1000.:
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Affinity purified

Target Information

Gene Symbol	CDK4
Alternative Names	CDK4 Cell division protein kinase 4 Crk3 Cyclin-dependent kinase 4 CMM3 p34/cdk4 PSK-J3

Database Links

Entrez Gene	1019
Protein Accession	P11802

Application

Application Notes	CDK4 antibody can be used in ELISA starting at 1: 10000, Western Blot starting at 1: 500 - 1: 2000, immunohistochemistry starting at 1:200, and immunofluorescence starting at 1:200 - 1:1000.:

Additional Information

Form	Liquid
Storage Instructions	Store CDK4 antibody undiluted at 4 ˚C. Do not freeze.
Storage Buffer	Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 0.2% gelatin.

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• Data sheet for OM275144