Western blot analysis using IKK gamma antibody against HepG2(1), PC-3(2) cell lysate.
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using IIKK gamma antibody with DAB staining.
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using IIKK gamma antibody with DAB staining.
Immunofluorescence analysis of CAL-27 cells using IKK gamma antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
Gene Summary
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.
Molecular Weight(MW)
48 kDa
Cellular Localization
Cytoplasm, Nucleus
Application
WB
Western blot analysis using IKK gamma antibody against HepG2(1), PC-3(2) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using IIKK gamma antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using IIKK gamma antibody with DAB staining.
ICC/IF
Immunofluorescence analysis of CAL-27 cells using IKK gamma antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
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