All products Antibodies IKK- gamma (phospho Ser31) Antibody

IKK- gamma (phospho Ser31) Antibody

Catalog Number：OM281800

  • Western blot analysis of extracts from 293 cells treated with TNF-a using Phospho-IKK- gamma (Ser31) Antibody. The lane on the right is treated with the antigen-specific peptide.

Product Profile

Product Name IKK- gamma (phospho Ser31) Antibody
Antibody Type Primary Antibodies
Product description 
Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly.1) Carter RS, Pennington KN, Ungurait BJ, Ballard DW (2003)J Biol Chem 278, 19642-8.
Immunogen 
IKK- gamma (phospho Ser31) antibody was raised against a peptide sequence around phosphorylation site of serine 31 (E-E-S (p)-P-L) derived from Human IKK-gamma.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB
Western Blot: 1:500~1:1000:
Species Reactivity

Human
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol IKBKG
Alternative Names
FIP-3
FIP3
I-kappa-B kinase gamma
IKBKG
IKKAP1
Molecular Weight(MW) 48 kDa
Tissue Specificity The antibody detects endogenous level of IKK- gamma only when phosphorylated at serine 31.

Database Links

Entrez Gene 8517
Protein Accession NP_001093326.2

Application

  • Application

    Western blot analysis of extracts from 293 cells treated with TNF-a using Phospho-IKK- gamma (Ser31) Antibody. The lane on the right is treated with the antigen-specific peptide.

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM281800
  • Price: $336.00
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