All products Antibodies Anti-IRF3 antibody

Anti-IRF3 antibody

Catalog Number:OM641939

  • Western blot analysis using IRF3 antibody against A431(1), COS-7(2), MCF-7(3)cell lysate.

  • Immunohistochemical analysis of paraffin-embedded lung cancer tissues using IRF3 antibody with DAB staining.

  • Immunofluorescence analysis of HepG2 cells using IRF3 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Product Profile

Product Name Anti-IRF3 antibody
Antibody Type Primary Antibodies
Immunogen
Polypeptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAICC/IFIHCWB

WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species Reactivity

HumanMouseRat

Concentration 1 mg/ml
Purification Protein A

Target Information

Gene Symbol IRF3
Gene Synonyms
IIAE7
Gene Full Name interferon regulatory factor 3
Gene Summary
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. [provided by RefSeq, Sep 2020]
Molecular Weight(MW) 47 KDa
Source Rabbit
Cellular Localization Cytoplasm, Mitochondrion, Nucleus

Application

  • WB

    Western blot analysis using IRF3 antibody against A431(1), COS-7(2), MCF-7(3)cell lysate.

  • IHC

    Immunohistochemical analysis of paraffin-embedded lung cancer tissues using IRF3 antibody with DAB staining.

  • ICC/IF

    Immunofluorescence analysis of HepG2 cells using IRF3 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500

Additional Information

Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

  • Catalog Number: OM641939
  • Price: $336.00
  • Discount Price
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  • Store: Out of stock
  • Lead time: 4~6 Week
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