All products Antibodies IRF3 Antibody

IRF3 Antibody

Catalog Number:OM282310

  • Immunohistochemistry staining of IRF3 in liver tissue using IRF3 Antibody.

Product Profile

Product Name IRF3 Antibody
Antibody Type Primary Antibodies
Product description
Interferon regulatory factor 3 (IRF3) is a trascription factor activated in response to various environmental stresses including viral infection and DNA-damaging agents. IRF3 can inhibit cell growth and plays a critical role in controling the expression of genes in the innate immune response. In unstimulated cells, IRF3 is present in the cytoplasm. Viral infection results in phosphorylation of IRF3, leading to its translocation to the nucleus, where it activates promoters Suitable for use in Western Blot and Immunohistochemistry (FFPE). Other applications not tested. Detects endogenous levels of human IRF3 at 57kD. Species Crossreactivity: monkey.
Immunogen
IRF3 antibody was raised against a synthetic peptide (KLH - coupled) corresponding to a region around residue 300 of IRF3 (Human).

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHCWB

IRF3 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.:
Species Reactivity

HumanMonkey

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol IRF3
Alternative Names
IRF3
Interferon regulatory factor 3
IRF-3

Database Links

Entrez Gene 3661
Protein Accession Q14653

Application

  • Application

    Immunohistochemistry staining of IRF3 in liver tissue using IRF3 Antibody.

Application Notes
IRF3 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.:

Additional Information

Form Liquid
Storage Instructions IRF3 antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.
Storage Buffer 10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

  • Catalog Number: OM282310
  • Price: $336.00
  • Discount Price
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  • Store: Out of stock
  • Lead time: 4~6 Week
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