All products Antibodies Anti-p53 antibody

Anti-p53 antibody

Catalog Number：OM641954

  • Western blot analysis using p53 antibody against HepG2 (1), A431 (2), PANC-1 (3) cell lysate.

  • Immunofluorescence analysis of HEK293 cells using p53 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Product Profile

Product Name Anti-p53 antibody
Antibody Type Primary Antibodies
Immunogen 
Polypeptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAICC/IFWB
WB:1:200-1:2000
ICC/IF:1:100-1:500
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Protein A

Target Information

Gene Symbol TP53
Gene Synonyms
TP53
P53
BCC7
LFS1
BMFS5
TRP53
Gene Full Name tumor protein p53
Gene Summary
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Molecular Weight(MW) 44 KDa
Source Rabbit
Cellular Localization Cytoplasm. Nucleus

Application

  • WB

    Western blot analysis using p53 antibody against HepG2 (1), A431 (2), PANC-1 (3) cell lysate.

  • ICC/IF

    Immunofluorescence analysis of HEK293 cells using p53 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes
WB:1:200-1:2000
ICC/IF:1:100-1:500

Additional Information

Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM641954
  • Price: $336.00
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  • Lead time: 4~6 Week

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