All products Antibodies Anti-stat3 antibody

Anti-stat3 antibody

Catalog Number：OM642126

  • Western blot analysis using stat3 antibody against Raji(1), MCF-7(2), Jurkat(3), HepG2(4) cell lysate.

  • Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using stat3 antibody with DAB staining.

  • Immunofluorescence analysis of A549 cells using stat3 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Product Profile

Product Name Anti-stat3 antibody
Antibody Type Primary Antibodies
Immunogen 
Polypeptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Protein A

Target Information

Gene Symbol STAT3
Gene Synonyms
APRF
HIES
ADMIO
ADMIO1
Gene Full Name signal transducer and activator of transcription 3
Gene Summary
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. This gene also plays a role in regulating host response to viral and bacterial infections. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. [provided by RefSeq, Aug 2020]
Molecular Weight(MW) 88 kDa（Observed:68 kDa）
Source Rabbit
Cellular Localization Cytoplasm, Nucleus

Application

  • WB

    Western blot analysis using stat3 antibody against Raji(1), MCF-7(2), Jurkat(3), HepG2(4) cell lysate.

  • IHC

    Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using stat3 antibody with DAB staining.

  • ICC/IF

    Immunofluorescence analysis of A549 cells using stat3 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500

Additional Information

Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM642126
  • Price: $336.00
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  • Lead time: 4~6 Week

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