All products Antibodies STAT3 Antibody

STAT3 Antibody

Catalog Number：OM292339

  • Immunofluorescence of STAT3 in human small intestine tissue with STAT3 antibody at 20 μg/ml.

  • Western blot analysis of STAT3 in human small intestine tissue lysate with STAT3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

  • Immunohistochemistry of STAT3 in human small intestine tissue with STAT3 antibody at 5 μg/ml.

Product Profile

Product Name STAT3 Antibody
Antibody Type Primary Antibodies
Product description 
STAT3 Antibody: STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, and STAT6), STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile. STAT3 signals are pivotal to the proliferation and differentiation of neural stem cells and also participate in neuronal regeneration and cancers of the nervous system.1) Schaefer TS, Sanders LK, and Nathans D. Cooperative transcriptional activity of Jun and Stat3b, a short form of Stat3. Proc. Natl. Acad. Sci. USA 1995; 92:9097-101.
Immunogen 
Rabbit polyclonal STAT3 antibody was raised against a 19amino acid peptide near the amino terminus of human STAT3. The immunogen is located within amino acids 170 - 220 of STAT3.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAIFIHC-PWB
STAT3 antibody can be used for detection of STAT3 by Western blot at 1 - 2 μg/mL.:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol STAT3
Alternative Names
STAT3 Antibody: APRF
HIES
APRF
Signal transducer and activator of transcription 3
Acute-phase response factor
Molecular Weight(MW) Predicted: 85 kDa
Sequence Similarities 2) Cat. No. 11-801 - Human Small Intestine Tissue Slide

Database Links

Entrez Gene 6774
Protein Accession NP_644805

Application

  • Application

    Immunofluorescence of STAT3 in human small intestine tissue with STAT3 antibody at 20 μg/ml.

  • Application

    Western blot analysis of STAT3 in human small intestine tissue lysate with STAT3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

  • Application

    Immunohistochemistry of STAT3 in human small intestine tissue with STAT3 antibody at 5 μg/ml.

Positive Control 1) Cat. No. 1308 - Human Small Intestine Tissue Lysate
Application Notes
STAT3 antibody can be used for detection of STAT3 by Western blot at 1 - 2 μg/mL.:

Additional Information

Form Liquid
Storage Instructions STAT3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Storage Buffer STAT3 Antibody is supplied in PBS containing 0.02% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM292339
  • Price: $336.00
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