All products Antibodies FADD Antibody

FADD Antibody

Catalog Number：OM278424

  • Antibody used in IHC on Human kidney.

  • Antibody used in WB on Human Thymus at 0.2-1 ug/ml.

Product Profile

Product Name FADD Antibody
Antibody Type Primary Antibodies
Product description 
The protein encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade.1) Thomas, L.R., et al., (2004) J. Biol. Chem. 279 (31), 32780-32785.
Immunogen 
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FADD.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

ELISAIHCWB
FADD antibody can be used for detection of FADD by ELISA at 1:62500. FADD antibody can be used for detection of FADD by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity

Human
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol FADD
Alternative Names
FADD
GIG3
MORT1
Molecular Weight(MW) 23 kDa

Database Links

Entrez Gene 8772
Protein Accession NP_003815

Application

  • Application

    Antibody used in IHC on Human kidney.

  • Application

    Antibody used in WB on Human Thymus at 0.2-1 ug/ml.

Positive Control 1) Cat. No. XBL-10426 - Fetal Thymus Tissue Lysate
Application Notes
FADD antibody can be used for detection of FADD by ELISA at 1:62500. FADD antibody can be used for detection of FADD by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:

Additional Information

Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store FADD antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM278424
  • Price: $336.00
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  • Lead time: 4~6 Week

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