Fadd Antibody

Product Profile

Product Name	Fadd Antibody
Antibody Type	Primary Antibodies
Product description	Fadd is apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
Immunogen	Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse Fadd.

Key Feature

Clonality	Polyclonal
Host Species	Rabbit
Tested Applications	ELISAWB
	Fadd antibody can be used for detection of Fadd by ELISA at 1:62500. Fadd antibody can be used for detection of Fadd by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity	Mouse
Concentration	1 mg/ml
Purification	Affinity purified

Target Information

Gene Symbol	FADD
Alternative Names	Fadd Mort1/FADD
Molecular Weight(MW)	23 kDa

Database Links

Entrez Gene	14082
Protein Accession	NP_034305

Application

Positive Control	1) SP2/0 Cell Lysate
Application Notes	Fadd antibody can be used for detection of Fadd by ELISA at 1:62500. Fadd antibody can be used for detection of Fadd by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:

Additional Information

Form	Liquid
Storage Instructions	For short periods of storage (days) store at 4˚C. For longer periods of storage, store Fadd antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer	Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.

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• Data sheet for OM278423