All products Antibodies NFKB2 Antibody

NFKB2 Antibody

Catalog Number：OM286138

  • Immunohistochemistry staining of NFKB2 in thymus tissue using NFKB2 Antibody.

Product Profile

Product Name NFKB2 Antibody
Antibody Type Primary Antibodies
Product description 
NFκB was originally identified as a factor that binds to the immunoglobulin kappa light chain enhancer in B cells. It was subsequently found in non-B cells in an inactive cytoplasmic form consisting of NFκB bound to IkB. NFκB was originally identified as a heterodimeric DNA binding protein complex consisting of p65 (RelA) and p50 (NFκB1) subunits. Other identified subunits include p52 (NFκB2), c-Rel, and RelB. The p65, cRel, and RelB subunits are responsible for transactivation. The p50 and p52 subunits possess DNA binding activity but limited ability to transactivate. p52 has been reported to form transcriptionally active heterodimers with the NFκB subunit p65, similar to p50/p65 heterodimers. The heterodimers of p52/p65 and p50/p65 are regulated by physical inactivation in the cytoplasm by an inhibitor called IkB-a. IkB-a binds to the p65 subunit, preventing nuclear localization and DNA binding. Low levels of p52 and p50 homodimers can also exist in cells.
Immunogen 
NFKB2 antibody was raised against a peptide near the N-Terminus of NFKB2 (Human).

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

ELISAIFIHCIPWB
NFKB2 antibody can be used in ELISA, and immunohistochemistry starting at 20 μg/mL.:
Species Reactivity

Human
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol NFKB2
Alternative Names
NFKB2
DNA-binding factor KBF2
LYT10
Oncogene Lyt-10
p52
LYT-10
NF-kB2
p105
H2TF1

Database Links

Entrez Gene 4791
Protein Accession Q00653

Application

  • Application

    Immunohistochemistry staining of NFKB2 in thymus tissue using NFKB2 Antibody.

Application Notes
NFKB2 antibody can be used in ELISA, and immunohistochemistry starting at 20 μg/mL.:

Additional Information

Form Liquid
Storage Instructions Store NFKB2 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Storage Buffer 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM286138
  • Price: $336.00
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  • Lead time: 4~6 Week

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