All products Antibodies NFkB p100 / p52 Antibody

NFkB p100 / p52 Antibody

Catalog Number：OM286111

  • Western blot analysis of lysed extracts from HT29 cells using NFκB-p100/p52 (Ab-872).

  • Top Image: Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using NFκB-p100/p52 (Ab-872). Bottom Image: Immunofluorescence staining of methanol-fixed HeLa cells using NFκB-p100/p52 (Ab-872).

Product Profile

Product Name NFkB p100 / p52 Antibody
Antibody Type Primary Antibodies
Product description 
NF-κ-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-κ-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.1) Shin HM, et al. (2006) EMBO J; 25 (1): 129-138. Li Q, et al. (2005) Proc Natl Acad Sci USA; 102 (35): 12425-12430. Chen C, et al. (2000) Mol Cell Biol; 20 (8): 2687-2695.
Immunogen 
NFkB-p100/p52 (Ab-872) antibody was raised against a peptide sequence around aa.870~874 (S-Q-S-V-E) derived from Human NFκB-p100/p52.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IFIHCWB
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:
Species Reactivity

HumanMouse
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol NFKB2
Alternative Names
p52
p105
H2TF1
LYT10
CVID10
LYT-10
NF-kB2
FLK1
VEGFR2
DNA-binding factor KBF2
Lymphocyte translocation chromosome 10
Lyt10
NFKB2
Molecular Weight(MW) 52, 120 kDa
Tissue Specificity This antibody detects endogenous level of total NFκB-p100/p52 protein.

Database Links

Entrez Gene 4791
Protein Accession NP_001070961.1

Application

  • Application

    Western blot analysis of lysed extracts from HT29 cells using NFκB-p100/p52 (Ab-872).

  • Application

    Top Image: Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using NFκB-p100/p52 (Ab-872). Bottom Image: Immunofluorescence staining of methanol-fixed HeLa cells using NFκB-p100/p52 (Ab-872).

Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM286111
  • Price: $336.00
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