All products Antibodies NFkB p100 / p52 Antibody

NFkB p100 / p52 Antibody

Catalog Number：OM286110

  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using NFκB-p100/p52 (Ab-870).

  • Western blot analysis of lysed extracts from HL60 cells using NFκB-p100/p52 (Ab-870).

Product Profile

Product Name NFkB p100 / p52 Antibody
Antibody Type Primary Antibodies
Product description 
NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-κ-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-κ-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.1) Qu Z, et al. (2004) J Biol Chem; 279 (43): 44563-72. Xiao G, et al. (2001) J Biol Chem 7 (2): 401-9.
Immunogen 
NFkB-p100/p52 (Ab-870) antibody was raised against a peptide sequence around aa.868~872 (Y-G-S-Q-S) derived from Human NFκB-p100/p52.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IHCWB
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
Species Reactivity

HumanMouse
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol NFKB2
Alternative Names
p52
p105
H2TF1
LYT10
CVID10
LYT-10
NF-kB2
FKHR
FOXO1A
DNA-binding factor KBF2
Lymphocyte translocation chromosome 10
Lyt10
NFKB2
Molecular Weight(MW) 120 kDa
Tissue Specificity This antibody detects endogenous level of total NFκB-p100/p52 protein.

Database Links

Entrez Gene 4791
Protein Accession NP_001070961.1

Application

  • Application

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using NFκB-p100/p52 (Ab-870).

  • Application

    Western blot analysis of lysed extracts from HL60 cells using NFκB-p100/p52 (Ab-870).

Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM286110
  • Price: $336.00
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