All products Antibodies PDX1 Antibody

PDX1 Antibody

Catalog Number：OM287780

  • Formalin-fixed and paraffin-embedded human testis tissue reacted with PDX1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

  • Western blot analysis of PDX1 using rabbit polyclonal PDX1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PDX1 gene (Lane 2).

Product Profile

Product Name PDX1 Antibody
Antibody Type Primary Antibodies
Product description 
PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in the gene encoding PDX1 are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).1) Ma,J., Carcinogenesis 29 (7), 1327-1333 (2008)
Immunogen 
This PDX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human PDX1.

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Species Reactivity

Human
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol PDX1
Alternative Names
Pancreas/duodenum homeobox protein 1
PDX-1
Glucose-sensitive factor
GSF
Insulin promoter factor 1
IPF-1
Insulin upstream factor 1
IUF-1
Islet/duodenum homeobox-1
IDX-1
Somatostatin-transactivating factor 1
STF-1
PDX1
IPF1
STF1
Molecular Weight(MW) 31 kDa

Database Links

Entrez Gene 3651
Protein Accession P52945

Application

  • Application

    Formalin-fixed and paraffin-embedded human testis tissue reacted with PDX1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

  • Application

    Western blot analysis of PDX1 using rabbit polyclonal PDX1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PDX1 gene (Lane 2).

Application Notes
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:

Additional Information

Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM287780
  • Price: $336.00
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