| Product Name | Rabbit anti-PDE4B polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DKFZp686F2182, DPDE4, MGC126529, PDE4B5, PDEIVB |
| Immunogen | The immunogen for anti-PDE4B antibody: synthetic peptide directed towards the middle region of human PDE4B |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PDE4B |
|---|---|
| Gene Synonyms | DKFZp686F2182 DPDE4 MGC126529 PDE4B5 PDEIVB |
| Gene Full Name | Phosphodiesterase 4B, cAMP-specific |
| Gene Summary | The specific function of this protein remains unknown.This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| Alternative Names | DKFZp686F2182 DPDE4 MGC126529 PDE4B5 PDEIVB |
| Molecular Weight(MW) | 64kDa |
| Sequence | 564 amino acids |
| Entrez Gene | 5142 |
|---|---|
| SwissProt ID | Q5TEK5 |
| Protein Accession | NP_001032416 |
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
