| Product Name | ABCG2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [2J39] to ABCG2The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
| Immunogen | human recombinant rHABCG2 protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 2J39 |
| Host Species | Mouse |
| Tested Applications | FACSIHC |
| Immunocytochemetry(1:100-1000)|FC(1:100-1000): |
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| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | EST157481 BCRP UAQTL1 CD338 GOUT1 BMDP BCRP1 MXR ABC15 ABCP MXR1 MRX ATP-binding cassette sub-family G (WHITE) member 2 A |
|---|---|
| Target | ABCG2 |
| Tissue Specificity | This antibody was selected for its ability to detect human ABCG2 by flow cytometry and immunocytochemistry. |
| Application Notes | Immunocytochemetry(1:100-1000)|FC(1:100-1000): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
