Mouse monoclonal antibody [DR-4-02] to DR4The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
Immunogen
Fusion protein containing the extracellular region of DR4
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Host Species
Mouse
Tested Applications
FACSICC/IFIP
Flow Cytometry: 1/50 - 1/100 Optimal dilution / concentration should be determined by the end user.:
FACS analysis of HeLa cells using DR4 antibody [DR-4-02].
Application Notes
Flow Cytometry: 1/50 - 1/100 Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.