| Product Name | DR4 antibody (Azide free) |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [HS101] to DR4The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant human TRAIL-R1 (DR4). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | FACSICC/IFIPFunctional Assay |
| Functional Assay: Inhibition (blocks TRAIL-R1 mediated killing if applied in solution).: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CD261 tumor necrosis factor receptor superfamily member 10a APO2 TNFRSF10A TRAILR1 |
|---|
| Application Notes | Functional Assay: Inhibition (blocks TRAIL-R1 mediated killing if applied in solution).: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least 1 year after receipt when stored at -20°C. |
| Storage Buffer | PBS containing 10% glycerol. |
