| Product Name | Granzyme B antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [GB7] to Granzyme BCytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant Granzyme B |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | GB7 |
| Host Species | Mouse |
| Tested Applications | IHC-PWB |
| Immunohistology - Paraffin: 1/50 - 1/200 Optimal dilution / concentration should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | granzyme B (granzyme 2 cytotoxic T-lymphocyte-associated serine esterase 1) CCPI CGL1 GZMB CTSGL1 CGL-1 CSP-B CTLA1 CSPB SECT HLP |
|---|---|
| Target | Granzyme B |
| Tissue Specificity | This antibody recognizes Granzyme B. |
| Application Notes | Immunohistology - Paraffin: 1/50 - 1/200 Optimal dilution / concentration should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | TRIS buffered saline containing 0.01% Thiomersal |
