Application
ELISA analysis of control antigen and antigen using LMNA antibody [4E7].Application
IHC-P analysis of human striated muscle tissues using LMNA antibody [4E7].Application
WB analysis of (1) Raw264.7, (2) PC-12, (3) THP-1, (4) A431, (5) MCF-7 and (6) Jurkat lysates using LMNA antibody [4E7].Application
WB analysis of human LMNA (a.a. 212-477) recombinant protein using LMNA antibody [4E7].| Product Name | Lamin A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [4E7] to Lamin AThe nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012] |
| Immunogen | The immunogen corresponding to human LMNA expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 4E7 |
| Host Species | Mouse |
| Tested Applications | ELISAIHCIHC-PWB |
| ELISA: 1/10000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Gene Synonyms | CDCD1 CMT2B1 IDC FPLD2 FPL LMNC PRO1 LFP LMNL1 HGPS LDP1 LMN1 FPLD CMD1A CDDC LGMD1B Antib |
|---|---|
| Target | Lamin A |
| Molecular Weight(MW) | 74 kDa (note) |
Application
ELISA analysis of control antigen and antigen using LMNA antibody [4E7].
Application
IHC-P analysis of human striated muscle tissues using LMNA antibody [4E7].
Application
WB analysis of (1) Raw264.7, (2) PC-12, (3) THP-1, (4) A431, (5) MCF-7 and (6) Jurkat lysates using LMNA antibody [4E7].
Application
WB analysis of human LMNA (a.a. 212-477) recombinant protein using LMNA antibody [4E7].| Application Notes | ELISA: 1/10000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | 4°C; -20°C for long term storage |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
