Application
Immunohistochemistry-Paraffin: Neurofibromin 1 Antibody (McNFn27b) - Immunohistochemical staining of adult human dorsal root ganglia| Product Name | Neurofibromin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal ( McNFn27 ) to neurofibrominNeurofibromin is a product of the tumor suppressor gene, Neurofibromatosis type I. Neurofibromin is known to have GTPase activity that modulates the ras pathway. The absence of or alteration of the neurofibromin protein may lead to Neurofibromatosis disease. This protein has not been purified, therefore, most of the information regarding this protein has been deduced from homology analysis of its gene sequence. |
| Immunogen | A highly conserved N-terminal peptide, corresponding to amino acids 27-41 of human neurofibromin. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | McNFn27 |
| Host Species | Mouse |
| Tested Applications | ELISAIHC-PIPWB |
| For IHC-P: Use at a dilution of 10-20 ug/ml. Antigen retrieval methods are not required for paraffin section IH. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | 162200 VRNF 4763 DKFZp686J1293 NFNS P21359 Neurofibromin WSS NF1 |
|---|---|
| Target | Neurofibromin |
| Cellular Localization | Cytoplasmic |
| Light Chain Type | kappa |
Application
Immunohistochemistry-Paraffin: Neurofibromin 1 Antibody (McNFn27b) - Immunohistochemical staining of adult human dorsal root ganglia| Application Notes | For IHC-P: Use at a dilution of 10-20 ug/ml. Antigen retrieval methods are not required for paraffin section IH. Optimal dilutions/concentrations should be determined by the researcher.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20 to -80 degrees C. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Ascitic fluid with 0.1% sodium azide |
