Application
Western Blot: Neurofibromin 1 Antibody (McNFn27a) - Specificity of Neurofibromin, using , in Schwann cells from embryonic knockout mice, adult human nerves and neonatal rat nerves| Product Name | Neurofibromin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal to neurofibrominNeurofibromin is a product of the tumor suppressor gene, Neurofibromatosis type I. Neurofibromin is known to have GTPase activity that modulates the ras pathway. The absence of or alteration of the neurofibromin protein may lead to Neurofibromatosis disease. This protein has not been purified, therefore, most of the information regarding this protein has been deduced from homology analysis of its gene sequence. |
| Immunogen | A highly conserved N-terminal peptide, corresponding to amino acids 27-41 of human neurofibromin. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | McNFn27a |
| Host Species | Mouse |
| Tested Applications | ELISAWB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | 162200 VRNF 4763 DKFZp686J1293 NFNS P21359 Neurofibromin WSS NF1 |
|---|---|
| Target | Neurofibromin |
| Tissue Specificity | This antibody is specific for full-length or truncated forms of neurofibromin. |
| Cellular Localization | Cytoplasmic |
| Light Chain Type | kappa |
Application
Western Blot: Neurofibromin 1 Antibody (McNFn27a) - Specificity of Neurofibromin, using , in Schwann cells from embryonic knockout mice, adult human nerves and neonatal rat nerves| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For long-term storage, keep at -20 °C. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | Ascitic fluid with 0.1% sodium azide |
