Application
Immunohistochemistry-Paraffin: Neurofibromin 1 Antibody (McNFn27b) - Immunohistochemical staining of adult human dorsal root ganglia.| Product Name | Neurofibromin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [McNFn27a] to NeurofibrominNeurofibromin is a product of the tumor suppressor gene, Neurofibromatosis type I. Neurofibromin is known to have GTPase activity that modulates the ras pathway. The absence of or alteration of the neurofibromin protein may lead to Neurofibromatosis disease. This protein has not been purified, therefore, most of the information regarding this protein has been deduced from homology analysis of its gene sequence. |
| Immunogen | Synthetic N-terminal peptide, corresponding to amino acids 27-41 of Human Neurofibromin. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | McNFn27a |
| Host Species | Mouse |
| Tested Applications | PurifyELISAIHC-PIP |
| AP: Use at an assay dependant dilution. ELISA: Use at an assay dependant dilution. IP: Use at an assay dependant dilution. IHC-P: Use at a concentration of 10 - 20 μg/ml. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | 162200 VRNF 4763 DKFZp686J1293 NFNS P21359 Neurofibromin WSS NF1 |
|---|---|
| Target | Neurofibromin |
| Tissue Specificity | This antibody is specific for full-length or truncated forms of neurofibromin. |
| Light Chain Type | kappa |
Application
Immunohistochemistry-Paraffin: Neurofibromin 1 Antibody (McNFn27b) - Immunohistochemical staining of adult human dorsal root ganglia.| Application Notes | AP: Use at an assay dependant dilution. ELISA: Use at an assay dependant dilution. IP: Use at an assay dependant dilution. IHC-P: Use at a concentration of 10 - 20 μg/ml. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Ascitic fluid with 0.1% sodium azide |
