Application
Immunofluorescence of GLUL in mouse brain tissue with GLUL antibody at 20 μg/mL.Application
Western blot analysis of GLUL in human brain tissue lysate with GLUL antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking buffer.Application
Immunohistochemistry of GLUL in mouse brain tissue with GLUL antibody at 5 μg/mL.| Product Name | GLUL Monoclonal Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GLUL Monoclonal Antibody: Glutamate ammonia ligase, glutamine synthase, glutamate decarboxylase, GLNS, GS, PIG43, PIG59, cell proliferation-inducing protein 59 |
| Product description | GLUL Monoclonal Antibody: Glutamate ammonia ligase (GLUL) belongs to the glutamine synthetase family and catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. GLUL is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Recent studies have suggested that elevated levels of GLUL may be an early marker for hepatocellular carcinoma.1) Wang Y, Kudoh J, Kubota R, et al. Chromosomal mapping of a family of human glutamine synthetase genes: functional gene (GLUL) on 1q25, pseudogene (GLULP) on 9p13, and three related genes (GLULL1, GLULL2, GLULL3) on 5q33, 11p15, and 11q24. |
| Immunogen | Mouse monoclonal GLUL antibody was raised against a 15 amino acid peptide near the amino terminus of human GLUL. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | ELISAIFIHC-PWB |
| GLUL antibody can be used for detection of GLUL by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GLUL |
|---|---|
| Alternative Names | GLUL Monoclonal Antibody: Glutamate ammonia ligase glutamine synthase glutamate decarboxylase GLNS GS PIG43 PIG59 cell proliferation-inducing protein 59 |
| Molecular Weight(MW) | Predicted: 41 kDa |
Application
Immunofluorescence of GLUL in mouse brain tissue with GLUL antibody at 20 μg/mL.
Application
Western blot analysis of GLUL in human brain tissue lysate with GLUL antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking buffer.
Application
Immunohistochemistry of GLUL in mouse brain tissue with GLUL antibody at 5 μg/mL.| Positive Control | 1) Cat. No. 1303 - Human Brain Tissue Lysate |
|---|---|
| Application Notes | GLUL antibody can be used for detection of GLUL by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | GLUL Monoclonal antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | GLUL Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide. |
