Application
Immunohistochemistry staining of Mucin 1 in breast tissue using Mucin 1 monoclonal Antibody.| Product Name | Mucin 1 Antibody, Monoclonal |
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| Antibody Type | Primary Antibodies |
| Product description | Human MUC-1 : This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. Also known as Cancer-associated Antigen 15-3 (CA15-3). |
| Immunogen | Mucin 1 monoclonal antibody was raised against a peptide located in the peptide repeat RPAP region of Mucin 1 (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | ELISAIFIHC |
| Mucin 1 antibody can be used in ELISA, and immunohistochemistry starting at 2.5 - 5 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MUC1 |
|---|---|
| Alternative Names | MUC1 CA15-3 CD227 Carcinoma-associated mucin CD227 antigen DF3 antigen Episialin Epithelial membrane antigen H23 antigen H23AG Krebs von den Lungen-6 MAM6 MUC1/ZD MUC-1/SEC Mucin-1 Pem KL-6 MUC-1/X Tumor-associated mucin Peanut-reactive |
| Tissue Specificity | Reactive to human MUC-1 peptide repeat RPAP region. |
Application
Immunohistochemistry staining of Mucin 1 in breast tissue using Mucin 1 monoclonal Antibody.| Application Notes | Mucin 1 antibody can be used in ELISA, and immunohistochemistry starting at 2.5 - 5 μg/mL. |
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| Form | Liquid |
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| Storage Instructions | For long term storage of Mucin 1 antibody add glycerol (40-50%) and store at -20 ˚C. For short term store at 4 ˚C. |
| Storage Buffer | TBS, pH 7.5, 0.05% sodium azide. |
