Monoclonal Antibody to Serine/Arginine Rich Splicing Factor 2 (SRSF2)
Antibody Type
Primary Antibodies
Immunogen
Recombinant SRSF2 (Thr14~Ser221) expressed in E.coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1, k
Host Species
Mouse
Tested Applications
ICC/IFIHCWB
WB:0.01-2µg/mL IHC:5-20µg/mL ICC/IF:5-20µg/mL
Species Reactivity
HumanRat
Concentration
1mg/ml
Purification
Protein A/G
Target Information
Gene Symbol
SRSF2
Gene Synonyms
SC35 PR264 SC-35 SFRS2 SFRS2A SRp30b
Gene Full Name
serine and arginine rich splicing factor 2
Gene Summary
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11. [provided by RefSeq, Sep 2010]