| Product Name | Anti-AIMP1/EMAP-II Recombinant Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a,k |
| Host Species | Mouse |
| Tested Applications | FCICC/IFWB |
| WB:1:1000 ICC/IF:1:100 FC:2-5ug for 1x106cells |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A/G |
| Gene Symbol | AIMP1 |
|---|---|
| Gene Synonyms | p43 HLD3 EMAP2 SCYE1 EMAPII |
| Gene Full Name | aminoacyl tRNA synthetase complex interacting multifunctional protein 1 |
| Gene Summary | The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008] |
| Molecular Weight(MW) | 34 kDa |
| Cellular Localization | Cytoplasm,Endoplasmic reticulum,Golgi apparatus,Nucleus,Secreted |
| Application Notes | WB:1:1000 ICC/IF:1:100 FC:2-5ug for 1x106cells |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term. |
| Storage Buffer | PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.. |
